The Human Pluripotent Stem Cell (HPSC) Core, established in 2008, is part of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics. An infrastructure and solid foundation has been created for the generation, differentiation, and gene editing of induced pluripotent stem cell (iPSC) lines. Using the CRISPR-CAS9 gene editing technology, isogenic control and disease-specific iPSC lines can be created for modeling human disease to study mechanism, development, and establish new therapeutic modalities. The Core provides enrichment training courses for 1) growth and maintenance of iPSC lines, 2) differentiation to mesoderm, endoderm or ectoderm, and 3) gene editing.
Jean Ann Maguire, PhD | Technical Director
maguirej@chop.edu
Hours | Location |
Open: Monday - Friday 1 PM - 2 PM |
3501 Civic Center Blvd, CTRB 10400 |
Name | Role | Phone | Location | |
---|---|---|---|---|
Jean Ann Maguire, PhD |
Technical Director
|
267-425-0901
|
maguirej@chop.edu
|
CTRB 10063
|
Services |
► Reagents – Media, Supplements (1) | |||
Name | Description | Price | |
---|---|---|---|
Advanced DMEM/F12 - 500 mL |
Gibco 12634010 Advanced DMEM/F-12 (Dulbecco's Modified Eagle Medium/Ham's F-12) is a widely used basal medium that allows the culture of mammalian cells with reduced Fetal Bovine Serum (FBS) supplementation. Compared to classic DMEM/F-12, serum supplementation can be reduced by 50–90% with no change in growth rate or morphology. |
Academic
$50.00
each
|