Translational Core

Overview of Services

The Translational Core Laboratory (TCL) at CHOP provides a variety of services ranging from laboratory testing to specimen special processing. We support investigators at CHOP, UPENN and Wistar for patient-orientated clinical research as well as preclinical animal and cell studies. External academic or industrial requests can also be accommodated.

Our services are focused on the following functional areas:

  • Clinical tests for research purpose.  We use several IVD (in vitro diagnostics)-qualified instruments to provide clinical tests for research purpose.  These tests include Complete Blood Counts (CBC), HbA1c, clinical chemistry (e.g., CMP, lipid panel, Na, creatinine, etc), and clinically-relevant immunoassays (e.g., CRP, Cystatin, insulin, Vitamin B12, PTH, cortisol, etc).  CBC and clinical chemistry assays can also be used for animal studies.  We also perform special assays like blood ABO typing, erythrocyte sedimentation rate (ESR), etc.
  • Biomarker discovery.  Our "ELISA Center" and PCR-based Gene Lab test protein and gene biomarkers that are not provided in the clinical setting.
  • Specimen processing.  We process samples for PBMC, DNA/RNA, and other special purposes according to your protocol.  We are also equipped with a super-low temperature SpeedVac that allows us to perform certain organic extractions (e.g., peptides to facilite their immuno-detection).
  • Short-term sample storage.  Liquid N2 and -80C space is available on a short-term basis to facilitate sample testing and/or processing.

 

Leadership & Staff

Nkecha Hughes | Research Associate                       Ronald Rubenstein | Faculty Advisor
267-426-5243                                                                 215-590-1281
hughesn@email.chop.edu                                             rubensteinr@email.chop.edu

 

Sarah Ellor | Research Technician
ellors@email.chop.edu, 215-590-1537

Courtney Schmidt | Research Technician
schmidtcn@email.chop.edu, 215-590-3218

 

Location and hours of operation

Hours   Location

Open:  Monday - Friday 9 AM - 5 PM

  3615 Civic Ctr Blvd
  Abramson Pediatric Research Building, Room 1203
  Philadelphia, PA 19104

Links and Resources

  1. Translational Core Laboratory (TCL) Webpage

Contacts

Name Role Phone Email Location
Nkecha Hughes
Research Associate
 
267-426-5243
 
hughesn@email.chop.edu
 
ARC 1203
 

Service list


Search available services: View: by category alphabetically
Clinical Chemistry (37)
Hematology (CBC) (4)
Immunoassay (9)
Molecular Biology (1)
Misc (3)
Special Assays (4)