The Translational Core Laboratory (TCL) at CHOP provides a variety of services ranging from laboratory testing to specimen special processing. We support investigators at CHOP, UPENN and Wistar for patient-orientated clinical research as well as preclinical animal and cell studies. External academic or industrial requests can also be accommodated.
Our services are focused on the following functional areas:
Nkecha Hughes | Research Lab Manager David Stokes | Technical Director
267-426-5243 215-590-4752
hughesn@chop.edu stokesdg@chop.edu
Courtney Schmidt | Research Technician
schmidtcn@chop.edu, 215-590-3218
Hours | Location |
Open: Monday - Friday 9 AM - 5 PM |
3501 Civic Ctr Blvd |
Name | Role | Phone | Location | |
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Nkecha Hughes |
Research Lab Manager
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267-426-5243
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hughesn@chop.edu
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CTRB A450-A
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Service list |
► Clinical Chemistry (37) | |||
Name | Description | Price | |
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Acetaminophen (ACET2) - Contact the Core Lab |
Species: human only Assay Range: 5 - 200 ug/mL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, Li-heparin plasma, EDTA plasma (K2/K3) Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Albumin (ALB2) - Test fee $14.20 + kit cost $54.16- Contact the Core Lab |
Species: human and animal Assay Range: 2 - 60 g/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will add kit cost to ilab request
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Inquire | |
Alkaline Phosphatase (ALP2) - Test fee $14.20 + kit cost $45- Contact the Core Lab |
Species: human and animal Assay Range: 5 - 1200 U/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will add kit cost to ilab request
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Inquire | |
Alanine Aminotransferase (ALTL) - Test fee $14.20 + kit cost $73- Contact the Core Lab |
Species: human & animals Assay Range: 5 - 700 U/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will add kit cost to ilab request
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Inquire | |
Aspartate Aminotransferase (ASTL) - Test fee $14.20 + kit cost $79.46 - Contact the Core Lab |
Species: human and animal Assay Range: 5 - 700 U/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will add kit cost to ilab request
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Inquire | |
Bilirubin, Direct (DBILI) - Test fee $14.20 + kit cost $159.39 - Contact the Core Lab |
Species: human and animal Assay Range: 0.2 - 10 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will add kit cost to ilab request
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Inquire | |
Bilirubin, Total (BILT3) - Contact the Core Lab |
Species: human and animal Assay Range: 0.15 - 35.1 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Basic Metabolic Panel (BMP) - Contact the Core Lab |
Panel: Na, K, Cl, CO2, BUN, Creatinine, Glucose, Calcium Species: human and animal Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Blood Urea Nitrogen (BUN) - Contact Core Lab (Serum/Plasma) |
Species: human and animal Assay Range: 1.4 - 112 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Calcium (CA2) Serum/Plasma - Contact Core Lab |
Species: human and animal Assay Range: 0.8 - 20.1 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Calcium (CA2) Urine - Contact Core Lab before collecting sample(s) |
Species: human and animal Assay Range: 0.8 - 30.1 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: urine Notes: Pricing includes testing fee, reagents and consumables Urine specimens should be collected in acid‑washed bottles 24‑hour specimens should be collected in containers containing 20‑30 mL of 6 mol/L HCl to prevent calcium salt precipitation Precipitated calcium salts may not be completely dissolved by the addition of HCl following urine collection TCL will generate an iLab request
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Inquire | |
Carbon Dioxide (CO2-L) Bicarbonate - Contact Core Lab |
Species: human and animal Assay Range: 2 - 50 mmol/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Chloride (Cl) - Contact Core Lab |
Species: human and animal Assay Range: Serum and Plasma 60 - 140 mmol/L; Urine 20 - 250 mmol/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, urine Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Cholesterol (CHOL2) - Contact Core Lab (included in Lipid Panel) |
Species: human and animal Assay Range: 3.86 - 800 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Comprehensive Metabolic Panel (CMP) - Contact Core Lab |
Panel: Na, K, Cl, CO2, BUN, Creatinine, Glucose, Calcium, Albumin, Total Protein, Total Bilirubin, ALP, ALT, AST Species: human and animal Platform: Roche Cobas c311 Automated: yes Compatible samples: Serum, Li-heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
C-Reactive Protein (CRPHS) - Contact the Core Lab |
Species: human only Assay Range: 0.15 - 20 mg/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Creatine Kinase (CK) - Contact Core Lab |
Species: human and animal Assay Range: 7 - 2000 U/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2/K3-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Creatinine, serum/plasma - Contact Core Lab |
Species: human and animal Assay Range: 0.06 - 30.5 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Creatinine, urine - Contact Core Lab |
Species: human and animal Assay Range: 1.1 - 610 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: urine Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Free Fatty Acids (FFA), Non-Esterified Fatty Acid, NEFA - Contact Core Lab |
Species: human and animal Assay Range: 0.01 - 4.00 mEq/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Gamma-glutamyl transferase (GGT) - Contact Core Lab |
Species: human and animal Assay Range: 3 - 1200 U/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Glucose - Contact Core Lab |
Species: human and animal Assay Range: 2 - 750 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, urine, CSF Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
HDL, high-density lipoprotein - Contact the Core Lab (included in Lipid Panel) |
Species: human & animals Assay Range: 3.09 - 150 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, Li-heparin plasma, EDTA plasma (K2/K3) Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Iron (Fe) - Contact Core Lab |
Species: human and animal Assay Range: 5 - 1000 ug/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Lactate - Contact Core Lab |
Species: human and animal Assay Range: 0.2 - 15.5 mmol/L Platform: Roche Cobas c311 Automated: yes Compatible samples: Na-Heparin Plasma, Na-Floride Plasma, K-Oxlate Plasma, CSF Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
LDL, low-density lipoprotein - Contact the Core Lab ( (included in Lipid Panel) |
Species: human and animal Assay Range: 3.87 - 549 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2/K3 EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Lipid Panel (Lipid Profile) - Contact the Core Lab |
Species: human and animal Panel: Cholesterol, HDL, LDL, Triglycerides Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Liver function panel - Test fee $17.25 + kit cost $459.55 (3month shelf life)- Contact the Core Lab |
Species: human and animal Panel: Albumin, ALP, ALT, AST, Direct Bilirubin, Total Bilirubin, Total Protein Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma Notes: Pricing includes testing fee, reagents and consumables TCL will add kit cost to ilab request
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Inquire | |
Magnesium - Contact Core Lab |
Species: human and animal Assay Range: 0.10 - 2.0 mmol/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, urine Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Phosphate - Contact Core Lab |
Species: human and animal Assay Range: Serum and Plasma - 0.31 - 20 mg/dL; Urine - 3.4 - 285 mg/dL Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, K2-EDTA plasma, urine Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Potassium (K) - Contact Core Lab |
Species: human and animal Assay Range: Serum and Plasma - 1.5 - 10 mmol/L; Urine - 3 - 100 mmol/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, urine Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Sodium (Na) - Contact Core Lab |
Species: human and animal Assay Range: Serum and plasma - 80 - 180 mmol/L; Urine 20 - 250 mmol/L Platform: Roche Cobas c311 Automated: yes Compatible samples: serum, lithium heparin plasma, urine Notes: Pricing includes testing fee, reagents and consumables TCL will generate an iLab request
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Inquire | |
Total Protein (Serum/plasma) - Contact Core Lab |
Species: human & animals Compatible samples: serum, EDTA plasma, heparin plasma Platform: Roche Cobas c311 Automated: yes |
Inquire | |
Triglycerides - Contact Core Lab (included in Lipid Panel) |
Species: human & animals Compatible samples: serum, EDTA plasma, heparin plasma Platform: Roche Cobas c311 Automated: yes Notes: part of the Lipid Panel |
Inquire | |
Urea (BUN), urine-Contact Core Lab for Pricing |
Species: human & animals Compatible samples: urine Platform: Roche Cobas c311 Automated: yes Notes: same test as BUN |
Inquire | |
Uric Acid (Serum and Plasma) - Contact Core Lab |
Species: human & animals Compatible samples: serum, EDTA plasma, heparin plasma Platform: Roche Cobas c311 Automated: yes |
Inquire | |
Uric Acid, urine - Contact Core Lab |
Species: human & animals Compatible samples: urine Platform: Roche Cobas c311 Automated: yes |
Inquire | |
► Hematology (CBC) (4) | |||
Name | Description | Price | |
CBC Only (without Diff or Reticulocytes) |
Compatible samples: human or animal EDTA whole blood, minimum 160 uL to run undiluted and 30 uL to run diluted (1:7). Platform: Sysmex XN-1000V Automated: yes |
Inquire | |
CBC + Differential + Reticulocytes |
Compatible samples: human or animal EDTA whole blood, minimum 125 uL to run undiluted and 30 uL to run diluted (1:7). Platform: Sysmex XN-1000V Automated: yes |
Inquire | |
CBC + Differential |
Compatible samples: human or animal EDTA whole blood, minimum 160 uL to run undiluted and 30 uL to run diluted (1:7). Platform: Sysmex XN-1000V Automated: yes |
Inquire | |
CBC + Reticulocytes -Undiluted Blood- minimum 160uL |
Compatible samples: human or animal EDTA whole blood, minimum 160 uL Platform: Sysmex XN-1000V Automated: yes |
Inquire | |
► Immunoassay (9) | |||
Name | Description | Price | |
Cobas c311 immunoassay service - Contact the Core Lab for pricing |
Minimum charge is 10 samples per test; Sample pretreatment (if needed) will be charged separately Kits will be charged separately Tests: Acetaminophen (ACET2), α-Amylase (AMYL2), α-Amylase Pancreatic (AMYLP), Apolipoprotein A1 (APO A1), Apolipoprotein B (APO B), Apolipoprotein C3, Beta-2 Microglobulin, Complement C3, C-reactive protein (CRP hs), Cystatin C, Ferritin, HBA1C, Homocystein (HCY), IgA, IgG, IgM, Lipoprotein (a) (LPA), Microalbumin (albumin in urine), Prealbumin
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Inquire | |
Cobas e411 immunoassay service - Contact the Core Lab for pricing |
Minimum charge is 10 samples; Sample pretreatment (if needed) will be charged separately; Kits will be charged separately
Tests: ACTH, Anti-CCP (Anti-cyclic citrullinated peptide), Anti-HBc, Anti-Müllerian hormone (AMH), Anti-Tg (Anti-Thyroglobulin), Anti-TPO (Anti-Thyroid Peroxidase), Anti-TSHR (Anti-TSH Receptor), CA 125, CA 15-3, CA 19-9, Calcitonin, CEA, CK-MB STAT, CMV IgG, CMV IgM, Cortisol, C-Peptide, CYFRA 21-1, DHEA-S, Digoxin, Estradiol, Ferritin, Folate, Folate (RBC), Free PSA, FSH, HAV antibodies (IgA and IgM), HAV IgM, HBc IgM, HBsAg, hCG (intact + β-hCG), hCG (intact), HCV Antibodies, HSV-1 IgG, HSV-2 IgG, Human epididymal protein 4 (HE4), Human Growth Hormone (hGH), Human sex hormone-binding globulin (SHBG), IgE, IGF-1, Insulin, Luteinizing Hormone (LH), Myoglobin, Osteocalcin (OCN), Parathyroid Hormone (PTH), pro-Brain Natriuretic Peptide (proBNP), Procalcitonin (PCT), Progesterone, Prolactin, Rubella IgG, Rubella IgM, Syphilis, T3, Testosterone, Thyroid Stimulating Hormone (TSH), Thyroxine (Free, FT4), Thyroxine (T4), Total PSA, Toxo IgG (IgG antibodies to Toxoplasma gondii), Toxo IgM (IgM antibodies to Toxoplasma gondii), Tri-iodothyronine (Free T3), Troponin I, Troponin T, T-Uptake (T4-Uptake), Vitamin B12, Vitamin D (25-OH), α-1-fetoprotein (AFP), β-CrossLaps (β-CTx) in Serum
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Inquire | |
C-peptide, human |
Run on Roche e411 Clinical Immunoanalyzer on a monthly basis; Compatible sample types: Serum, EDTA plasma, heparin plasma; Minimum volume: 150 uL. Notes: Minimum of 30 samples to run test
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Inquire | |
Insulin, human - Contact the Core Lab for pricing |
Run on Roche e411 Clinical Immunoanalyzer; Compatible sample types: serum, EDTA plasma, heparin plasma; Minimum volume: 150 uL. Notes: Minimum of 30 samples to run test
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Inquire | |
ELISA service - Contact the Core Lab |
Minimum 30 samples Sample pretreatment (if needed) will be charged separately; We use commercially available kits. Kits will be charged separately. Kit validation can be performed. Pricing based on level of validation. Lot-to-lot kit comparison for data bridging can be performed for an additional charge.
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Inquire | |
ELISA testing charge |
We use commercially available kits. Kit validation can be performed. Lot-to-lot kit comparison for data bridging can be performed. |
Inquire | |
ELISA two-day assay service charge |
Minimum charge is 30 samples; Sample pretreatment (if needed) will be charged separately; Kits will be charged separately. Tests include active GLP-1, MSD U-plex assays, kynurenine/tryptophan ratio assay, etc |
Inquire | |
Ella 1-plex (1 x 72) service |
"Automated ELISA", 72 samples per kit; Minimum charge is 40 samples; Sample pretreatment (if needed) will be charged separately; Kits will be charged separately. Multiplex assay kits are available.
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Inquire | |
Luminex Testing Service - Contact the Core Lab |
Multiplex capability, up to 50-plex. Low sample consumption. Some assays are as sensiviity as ELISA. Most assays are for screening purpose.
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Inquire | |
► Molecular Biology (1) | |||
Name | Description | Price | |
RNA extraction-Contact the Core Lab for pricing |
Samples: PAXgene or Tempus blood tube, or other cells. |
Inquire | |
► Misc (3) | |||
Name | Description | Price | |
DNA Extraction |
Samples: blood, saliva, cell pellet, tissue, etc Characterization by Nanodrop, Qubit or PicoGreen |
Inquire | |
DNA/RNA co-extraction |
Extracted DNA and RNA are in separate tubes. |
Inquire | |
Real Time PCR (qPCR) Service |
Set up and run the 384-well plate |
Inquire | |
► Special Assays (4) | |||
Name | Description | Price | |
BCA assay, labor charge | Inquire | ||
Organic extraction |
We have a super low temperature speedvac which allows organic extraction of certain small molecules such as peptides. |
Inquire | |
Special assays |
These include ABO blood typing, erythrocyte sedimentation rate (ESR), pyruvate, citrate, beta-Hydroxybutyrate and so on. |
Inquire | |
Total Bile Acids, labor charge | Inquire |